I said this before but I'll say it again:
make your Poké Pelago as useful as possible. Do not ignore it. It may seem gimmicky at first, but it's got some powerful tools available.
Isle Abeens: You need beans to upgrade your islands and enhance them at the same time, so getting this out of the way first will net you a very nice flow of beans. As an added bonus, you'll attract some unique Pokémon you can add to your box, since you need at least 90 boxed Pokémon to fully upgrade your islands as well.
Isle Aplenny: This is the only place in the game where you can grow berries. Thankfully, it's all automated, and there's no more having to water or weed or anything. Paying beans lets the berries grow faster, and fully upgrading it lets you maintain 18 plants at once.
Isle Aphun: This place offers goodies like shards (which can be exchanged for all-important bottle caps), evolution stones, high-value vendor trash and even gold bottle caps. It's a bit time-consuming (taking a day to work), but paying beans speeds things up.
Isle Evelup: Lets you EV train. It's slow, but you can train several Pokémon up at once, and you don't have to sink a bunch of time in on one 'mon. It also allows precision on those tricky EV spreads (the ones other than 252/252/4) and lets you train and have a life at the same time. At level 3, those drinks furnish four EVs each, and if you pay beans it cuts the time in half.
Isle Avue: It increases happiness (making it useful for Return attackers/Draco Meteor), but it's also an egg incubator. Meaning no more running in circles for hours straight. Paying beans increases happiness faster and hatches eggs faster.
In other words, fukkin' use it, boyos.