This thing saved me from death so many times I've lost count. I remember one shotting deathclaws with this monster of a gun. I think you have to aim for the head though, or it's just a random critical hit that does the job. Not sure, haven't played in a while. The holorifle is the greatest asset to come out of dead money, followed closely by the cosmic-superheated-piece-of-shit-knife which does ridiculous burn damage. Need to survive in the Mojave desert? These are the guns for you.
The balder side sword is the citizen kane of all purpose weaponry. It is a tool of murder for a pure DEX build, and has FIXED damage. That means having armour won't count for squat when this sword pierces through your vtial organs. I have solo'd too many bosses with this weapon it's not even funny, and solo'ing bosses in this game is supposed to be HARD. Nothing will save you from this thing.
Ah, the M4A1-S. What a beauty you are. With only 20 bullets in a magazine and 60 in the total reserve, you better make those shots count, amigo. Where this weapon shines is it's accuracy and low recoil making it perfect for the double tapping headshot tactician that you've always wanted to be in CS:GO. And it's even cheaper than it's unsilenced counterpart, the M4A4. Do yourself a favour and do NOT remove the silencer as it invalidates everything about the gun and the recoil is huge. Don't be a silly.